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The role of plasma membrane STIM1 and Ca(2 +)entry in platelet aggregation. STIM1 binds to novel proteins in human platelets
Ca(2 +) elevation is essential to platelet activation. STIM1 senses Ca(2 +) in the endoplasmic reticulum and activates Orai channels allowing store-operated Ca(2 +) entry (SOCE). STIM1 has also been reported to be present in the plasma membrane (PM) with its N-terminal region exposed to the outside...
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| Main Authors: | , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
Elsevier Science Ltd
2014
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4062937/ https://ncbi.nlm.nih.gov/pubmed/24308967 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cellsig.2013.11.025 |
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