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N-Demethylation and N-oxidation of imipramine in rat thoracic aortic endothelial cells
The aim of this study was to examine whether cultured rat thoracic aortic endothelial cells (TAECs) have the ability to metabolize the tertiary amine, imipramine. In rat TAECs, imipramine was biotransformed into N-demethylate and N-oxide by cytochrome P450 (CYP) and flavin-containing monooxygenase (...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Springer US
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4062819/ https://ncbi.nlm.nih.gov/pubmed/24647745 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11626-014-9739-0 |
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