Activation of K(2)P channel–TREK1 mediates the neuroprotection induced by sevoflurane preconditioning

BACKGROUND: Preconditioning with volatile anaesthetic agents induces tolerance to focal cerebral ischaemia, although the underlying mechanisms have not been clearly defined. The present study analyses whether TREK-1, a two-pore domain K(+) channel and target for volatile anaesthetics, plays a role i...

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Bibliographic Details
Main Authors: Tong, L., Cai, M., Huang, Y., Zhang, H., Su, B., Li, Z., Dong, H.
Format: Artigo
Language:Inglês
Published: Oxford University Press 2014
Subjects:
Neurosciences and Neuroanaesthesia
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4062297/
https://ncbi.nlm.nih.gov/pubmed/24154701
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/bja/aet338
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