Interrogating causal pathways linking genetic variants, small molecule metabolites, and circulating lipids

BACKGROUND: Emerging technologies based on mass spectrometry or nuclear magnetic resonance enable the monitoring of hundreds of small metabolites from tissues or body fluids. Profiling of metabolites can help elucidate causal pathways linking established genetic variants to known disease risk factor...

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Détails bibliographiques
Auteurs principaux: Shin, So-Youn, Petersen, Ann-Kristin, Wahl, Simone, Zhai, Guangju, Römisch-Margl, Werner, Small, Kerrin S, Döring, Angela, Kato, Bernet S, Peters, Annette, Grundberg, Elin, Prehn, Cornelia, Wang-Sattler, Rui, Wichmann, H-Erich, de Angelis, Martin Hrabé, Illig, Thomas, Adamski, Jerzy, Deloukas, Panos, Spector, Tim D, Suhre, Karsten, Gieger, Christian, Soranzo, Nicole
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2014
Sujets:
Research
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC4062056/
https://ncbi.nlm.nih.gov/pubmed/24678845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gm542
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