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Interrogating causal pathways linking genetic variants, small molecule metabolites, and circulating lipids

BACKGROUND: Emerging technologies based on mass spectrometry or nuclear magnetic resonance enable the monitoring of hundreds of small metabolites from tissues or body fluids. Profiling of metabolites can help elucidate causal pathways linking established genetic variants to known disease risk factor...

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Main Authors: Shin, So-Youn, Petersen, Ann-Kristin, Wahl, Simone, Zhai, Guangju, Römisch-Margl, Werner, Small, Kerrin S, Döring, Angela, Kato, Bernet S, Peters, Annette, Grundberg, Elin, Prehn, Cornelia, Wang-Sattler, Rui, Wichmann, H-Erich, de Angelis, Martin Hrabé, Illig, Thomas, Adamski, Jerzy, Deloukas, Panos, Spector, Tim D, Suhre, Karsten, Gieger, Christian, Soranzo, Nicole
פורמט: Artigo
שפה:Inglês
יצא לאור: BioMed Central 2014
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גישה מקוונת:https://ncbi.nlm.nih.gov/pmc/articles/PMC4062056/
https://ncbi.nlm.nih.gov/pubmed/24678845
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gm542
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