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Optimizing the treatment of BRAF mutant melanoma

Selective inhibitors of the kinases BRAF and MEK for the treatment of patients with otherwise refractory BRAF mutant melanoma have demonstrated impressive efficacy, and combination treatment with these agents may prove to be even more effective. However, these drugs are not curative, mainly because...

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Detalhes bibliográficos
Autor principal: Settleman, Jeff
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4062054/
https://ncbi.nlm.nih.gov/pubmed/25031620
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/gm547
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