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Biology and treatment of BRAF mutant metastatic melanoma
BRAF inhibitors were among the first systemic therapies to show clinical benefit in metastatic melanoma. Here, we review the spectrum of BRAF mutations in melanoma, their role in oncogenesis, clinicopathological associations and response to treatment. The differing biology and clinical features of V...
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| Pubblicato in: | Melanoma Manag |
|---|---|
| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Future Medicine Ltd
2016
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6097549/ https://ncbi.nlm.nih.gov/pubmed/30190871 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/mmt.15.38 |
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