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Biology and treatment of BRAF mutant metastatic melanoma
BRAF inhibitors were among the first systemic therapies to show clinical benefit in metastatic melanoma. Here, we review the spectrum of BRAF mutations in melanoma, their role in oncogenesis, clinicopathological associations and response to treatment. The differing biology and clinical features of V...
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| Publicado no: | Melanoma Manag |
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| Main Authors: | , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Future Medicine Ltd
2016
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6097549/ https://ncbi.nlm.nih.gov/pubmed/30190871 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2217/mmt.15.38 |
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