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Inhibition of Mycobacterium tuberculosis PknG by non-catalytic rubredoxin domain specific modification: reaction of an electrophilic nitro-fatty acid with the Fe–S center

PknG from Mycobacterium tuberculosis is a Ser/Thr protein kinase that regulates key metabolic processes within the bacterial cell as well as signaling pathways from the infected host cell. This multidomain protein has a conserved canonical kinase domain with N- and C-terminal flanking regions of unc...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Gil, Magdalena, Graña, Martín, Schopfer, Francisco J., Wagner, Tristan, Denicola, Ana, Freeman, Bruce A., Alzari, Pedro M., Batthyány, Carlos, Durán, Rosario
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: 2013
Gaiak:
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC4061738/
https://ncbi.nlm.nih.gov/pubmed/23792274
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2013.06.021
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