PknG senses amino acid availability to control metabolism and virulence of Mycobacterium tuberculosis

Sensing and response to changes in nutrient availability are essential for the lifestyle of environmental and pathogenic bacteria. Serine/threonine protein kinase G (PknG) is required for virulence of the human pathogen Mycobacterium tuberculosis, and its putative substrate GarA regulates the tricar...

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Udgivet i:PLoS Pathog
Main Authors: Rieck, Barbara, Degiacomi, Giulia, Zimmermann, Michael, Cascioferro, Alessandro, Boldrin, Francesca, Lazar-Adler, Natalie R., Bottrill, Andrew R., le Chevalier, Fabien, Frigui, Wafa, Bellinzoni, Marco, Lisa, María-Natalia, Alzari, Pedro M., Nguyen, Liem, Brosch, Roland, Sauer, Uwe, Manganelli, Riccardo, O’Hare, Helen M.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2017
Fag:
Research Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5448819/
https://ncbi.nlm.nih.gov/pubmed/28545104
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.ppat.1006399
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