ACTIVATION OF VASCULAR ENDOTHELIAL NITRIC OXIDE SYNTHASE AND HEME OXYGENASE-1 EXPRESSION BY ELECTROPHILIC NITRO-FATTY ACIDS

Reactive oxygen species mediate a decrease in nitric oxide (NO) bioavailability and endothelial dysfunction, with secondary oxidized and nitrated byproducts of these reactions contributing to the pathogenesis of numerous vascular diseases. While oxidized lipids and lipoproteins exacerbate inflammato...

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Detalhes bibliográficos
Main Authors: Khoo, Nicholas K.H., Rudolph, Volker, Cole, Marsha P., Golin-Bisello, Franca, Schopfer, Francisco J., Woodcock, Steven R., Batthyany, Carlos, Freeman, Bruce A.
Formato: Artigo
Idioma:Inglês
Publicado em: 2009
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2818734/
https://ncbi.nlm.nih.gov/pubmed/19857569
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.freeradbiomed.2009.10.046
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