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Loss of the desmosomal cadherin desmoglein-2 suppresses colon cancer cell proliferation through EGFR signaling

Desmosomal cadherins mediate cell–cell adhesion in epithelial tissues and have been known to be altered in cancer. We have previously shown that one of the two intestinal epithelial desmosomal cadherins, desmocollin-2 (Dsc2) loss promotes colonic epithelial carcinoma cell proliferation and tumor for...

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Detalhes bibliográficos
Main Authors: Kamekura, R, Kolegraff, KN, Nava, P, Hilgarth, RS, Feng, M, Parkos, CA, Nusrat, A
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4061272/
https://ncbi.nlm.nih.gov/pubmed/24166502
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2013.442
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