The desmosomal cadherin desmoglein-3 acts as a keratinocyte anti-stress protein via suppression of p53

Desmoglein-3 (Dsg3), the Pemphigus Vulgaris (PV) antigen (PVA), plays an essential role in keratinocyte cell–cell adhesion and regulates various signaling pathways involved in the progression and metastasis of cancer where it is upregulated. We show here that expression of Dsg3 impacts on the expres...

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Detalhes bibliográficos
Publicado no:Cell Death Dis
Main Authors: Rehman, Ambreen, Cai, Yang, Hünefeld, Christian, Jedličková, Hana, Huang, Yunying, Teck Teh, Muy, Sharif Ahmad, Usama, Uttagomol, Jutamas, Wang, Ying, Kang, Angray, Warnes, Gary, Harwood, Catherine, Bergamaschi, Daniele, Kenneth Parkinson, Eric, Röcken, Martin, Wan, Hong
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6776551/
https://ncbi.nlm.nih.gov/pubmed/31582719
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41419-019-1988-0
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