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EGFR and ADAMs Cooperate to Regulate Shedding and Endocytic Trafficking of the Desmosomal Cadherin Desmoglein 2

Regulation of classic cadherins plays a critical role in tissue remodeling during development and cancer; however, less attention has been paid to the importance of desmosomal cadherins. We previously showed that EGFR inhibition results in accumulation of the desmosomal cadherin, desmoglein 2 (Dsg2)...

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Main Authors: Klessner, Jodi L., Desai, Bhushan V., Amargo, Evangeline V., Getsios, Spiro, Green, Kathleen J.
Formáid: Artigo
Teanga:Inglês
Foilsithe: The American Society for Cell Biology 2009
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC2613100/
https://ncbi.nlm.nih.gov/pubmed/18987342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E08-04-0356
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