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Metabotropic glutamate receptor 1 (mGluR1) mediates melanocyte transformation via transactivation of IGF-1 Receptor

Our lab previously described the oncogenic properties of metabotropic glutamate receptor 1 (mGluR1) in melanocytes. mGluR1 transformed immortalized mouse melanocytes in vitro and induced vigorous tumor formation in vivo. Subsequently, we observed the activation of PI3K/AKT in mGluR1-mediated melanoc...

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Detaylı Bibliyografya
Asıl Yazarlar: Teh, Jessica L.F., Shah, Raj, Shin, Seung-Shick, Wen, Yu, Mehnert, Janice M., Goydos, James, Chen, Suzie
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: 2014
Konular:
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4061214/
https://ncbi.nlm.nih.gov/pubmed/24628914
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/pcmr.12237
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