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Oncogenic activities of metabotropic glutamate receptor 1 (Grm1) in melanocyte transformation
Previously, we reported a transgenic mouse line, TG-3, that develops spontaneous melanoma with 100% penetrance. We demonstrated that ectopic expression of Grm1 in melanocytes was sufficient to induce melanoma in vivo. In this present study, the transforming properties of Grm1 in two cultured immorta...
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| Main Authors: | , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2854004/ https://ncbi.nlm.nih.gov/pubmed/18435704 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1755-148X.2008.00452.x |
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