Signal-induced degradation of I kappa B alpha requires site-specific ubiquitination.

Eitemau Tebyg

• Coupling of a signal response domain in I kappa B alpha to multiple pathways for NF-kappa B activation.
  gan: Brockman, J A, et al.
  Cyhoeddwyd: (1995)
• Signal-induced degradation of I(kappa)B(alpha): association with NF-kappaB and the PEST sequence in I(kappa)B(alpha) are not required.
  gan: Van Antwerp, D J, et al.
  Cyhoeddwyd: (1996)
• Stimulation-dependent I kappa B alpha phosphorylation marks the NF-kappa B inhibitor for degradation via the ubiquitin-proteasome pathway.
  gan: Alkalay, I, et al.
  Cyhoeddwyd: (1995)
• Activation of NF-kappa B requires proteolysis of the inhibitor I kappa B-alpha: signal-induced phosphorylation of I kappa B-alpha alone does not release active NF-kappa B.
  gan: Lin, Y C, et al.
  Cyhoeddwyd: (1995)
• Three NF-kappa B sites in the I kappa B-alpha promoter are required for induction of gene expression by TNF alpha.
  gan: Ito, C Y, et al.
  Cyhoeddwyd: (1994)