Domain organization of I kappa B alpha and sites of interaction with NF-kappa B p65.

Antzeko izenburuak

• I(kappa)B(gamma) inhibits DNA binding of NF-kappaB p50 homodimers by interacting with residues that contact DNA.
  nork: Bell, S, et al.
  Argitaratua: (1996)
• I kappa B/MAD-3 masks the nuclear localization signal of NF-kappa B p65 and requires the transactivation domain to inhibit NF-kappa B p65 DNA binding.
  nork: Ganchi, P A, et al.
  Argitaratua: (1992)
• Coupling of a signal response domain in I kappa B alpha to multiple pathways for NF-kappa B activation.
  nork: Brockman, J A, et al.
  Argitaratua: (1995)
• Activation of NF-kappa B requires proteolysis of the inhibitor I kappa B-alpha: signal-induced phosphorylation of I kappa B-alpha alone does not release active NF-kappa B.
  nork: Lin, Y C, et al.
  Argitaratua: (1995)
• Proteolytic degradation of MAD3 (I kappa B alpha) and enhanced processing of the NF-kappa B precursor p105 are obligatory steps in the activation of NF-kappa B.
  nork: Mellits, K H, et al.
  Argitaratua: (1993)