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Signal-induced degradation of I kappa B alpha requires site-specific ubiquitination.

The inhibitor protein I kappa B alpha controls the nuclear import of the transcription factor NF-kappa B. The inhibitory activity of I kappa B alpha is regulated from the cytoplasmic compartment by signal-induced proteolysis. Previous studies have shown that signal-dependent phosphorylation of serin...

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Bibliografische gegevens
Hoofdauteurs: Scherer, D C, Brockman, J A, Chen, Z, Maniatis, T, Ballard, D W
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 1995
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Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC40611/
https://ncbi.nlm.nih.gov/pubmed/7479976
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