Discovery and Synthesis of C-Nucleosides as Potential New Anti-HCV Agents

[Image: see text] Nucleoside analogues have long been recognized as prospects for the discovery of direct acting antivirals (DAAs) to treat hepatitis C virus because they have generally exhibited cross-genotype activity and a high barrier to resistance. C-Nucleosides have the potential for improved...

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主要な著者: Draffan, Alistair G., Frey, Barbara, Pool, Brett, Gannon, Carlie, Tyndall, Edward M., Lilly, Michael, Francom, Paula, Hufton, Richard, Halim, Rosliana, Jahangiri, Saba, Bond, Silas, Nguyen, Van T. T., Jeynes, Tyrone P., Wirth, Veronika, Luttick, Angela, Tilmanis, Danielle, Thomas, Jesse D., Pryor, Melinda, Porter, Kate, Morton, Craig J., Lin, Bo, Duan, Jianmin, Kukolj, George, Simoneau, Bruno, McKercher, Ginette, Lagacé, Lisette, Amad, Ma’an, Bethell, Richard C., Tucker, Simon P.
フォーマット: Artigo
言語:Inglês
出版事項: American Chemical Society 2014
オンライン･アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060939/
https://ncbi.nlm.nih.gov/pubmed/24944743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml500077j
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