Discovery and Synthesis of C-Nucleosides as Potential New Anti-HCV Agents

[Image: see text] Nucleoside analogues have long been recognized as prospects for the discovery of direct acting antivirals (DAAs) to treat hepatitis C virus because they have generally exhibited cross-genotype activity and a high barrier to resistance. C-Nucleosides have the potential for improved...

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Main Authors: Draffan, Alistair G., Frey, Barbara, Pool, Brett, Gannon, Carlie, Tyndall, Edward M., Lilly, Michael, Francom, Paula, Hufton, Richard, Halim, Rosliana, Jahangiri, Saba, Bond, Silas, Nguyen, Van T. T., Jeynes, Tyrone P., Wirth, Veronika, Luttick, Angela, Tilmanis, Danielle, Thomas, Jesse D., Pryor, Melinda, Porter, Kate, Morton, Craig J., Lin, Bo, Duan, Jianmin, Kukolj, George, Simoneau, Bruno, McKercher, Ginette, Lagacé, Lisette, Amad, Ma’an, Bethell, Richard C., Tucker, Simon P.
Formato: Artigo
Idioma:Inglês
Publicado em: American Chemical Society 2014
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060939/
https://ncbi.nlm.nih.gov/pubmed/24944743
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml500077j
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