Novel and High Affinity Fluorescent Ligands for the Serotonin Transporter Based on (S)-Citalopram

[Image: see text] Novel rhodamine-labeled ligands, based on (S)-citalopram, were synthesized and evaluated for uptake inhibition at the human serotonin, dopamine, and norepinephrine transporters (hSERT, hDAT, and hNET, respectively) and for binding at SERT, in transiently transfected COS7 cells. Com...

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Hauptverfasser: Kumar, Vivek, Rahbek-Clemmensen, Troels, Billesbølle, Christian B., Jorgensen, Trine Nygaard, Gether, Ulrik, Newman, Amy Hauck
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Chemical Society 2014
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060933/
https://ncbi.nlm.nih.gov/pubmed/24944746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml5000806
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