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Novel and High Affinity Fluorescent Ligands for the Serotonin Transporter Based on (S)-Citalopram

[Image: see text] Novel rhodamine-labeled ligands, based on (S)-citalopram, were synthesized and evaluated for uptake inhibition at the human serotonin, dopamine, and norepinephrine transporters (hSERT, hDAT, and hNET, respectively) and for binding at SERT, in transiently transfected COS7 cells. Com...

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Main Authors: Kumar, Vivek, Rahbek-Clemmensen, Troels, Billesbølle, Christian B., Jorgensen, Trine Nygaard, Gether, Ulrik, Newman, Amy Hauck
格式: Artigo
語言:Inglês
出版: American Chemical Society 2014
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060933/
https://ncbi.nlm.nih.gov/pubmed/24944746
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/ml5000806
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