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Characterization of the Deoxyguanosine–Lysine Cross-Link of Methylglyoxal
[Image: see text] Methylglyoxal is a mutagenic bis-electrophile that is produced endogenously from carbohydrate precursors. Methylglyoxal has been reported to induce DNA–protein cross-links (DPCs) in vitro and in cultured cells. Previous work suggests that these cross-links are formed between guanin...
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| Main Authors: | , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
American Chemical
Society
2014
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| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4060920/ https://ncbi.nlm.nih.gov/pubmed/24801980 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/tx500068v |
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