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Mechanisms underlying differential effectiveness of memantine and ketamine in rapid antidepressant responses
Ketamine is an NMDA receptor (NMDAR) antagonist that elicits rapid antidepressant responses in patients with treatment-resistant depression. However, ketamine can also produce psychotomimetic effects that limit its utility as an antidepressant, raising the question of whether the clinically tolerate...
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| Main Authors: | , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4060670/ https://ncbi.nlm.nih.gov/pubmed/24912158 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1323920111 |
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