Novel Gene Variants Predict Serum Levels of the Cytokines IL-18 and IL-1ra in Older Adults

Activation of inflammatory pathways measured by serum inflammatory markers such as interleukin-18 (IL-18) and interleukin-1 receptor antagonist (IL-1ra) is strongly associated with the progression of chronic disease states in older adults. Given that these serum cytokine levels are in part a heritab...

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Main Authors: Matteini, AM, Li, J, Lange, EM, Tanaka, T, Lange, LA, Tracy, RP, Wang, Y, Biggs, ML, Arking, DE, Fallin, MD, Chakravarti, A, Psaty, BM, Bandinelli, S, Ferrucci, L, Reiner, AP, Walston, JD
Formato: Artigo
Idioma:Inglês
Publicado: 2013
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060632/
https://ncbi.nlm.nih.gov/pubmed/24182552
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cyto.2013.10.002
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