Fibrinogen and IL6 Gene Variants and IL-6 Levels in Relation to Plasma Fibrinogen Concentration and Cardiovascular Disease Risk in the Cardiovascular Health Study

BACKGROUND: The inflammatory cytokine interleukin-6 (IL-6) is a main regulator of fibrinogen synthesis, though its interaction with fibrinogen genes (FGA, FGB, FGG) in relation to CVD risk is not well-studied in humans. METHODS AND RESULTS: We investigated joint associations of common fibrinogen and...

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Bibliografiske detaljer
Main Authors: Carty, CL, Heagerty, P, Heckbert, SR, Jarvik, GP, Lange, LA, Cushman, M, Tracy, RP, Reiner, AP
Format: Artigo
Sprog:Inglês
Udgivet: 2010
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC2946374/
https://ncbi.nlm.nih.gov/pubmed/20059469
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1469-1809.2009.00551.x
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