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Fibrinogen and clot-related phenotypes determined by fibrinogen polymorphisms: Independent and IL-6-interactive associations

Interleukin-6 (IL-6) induces the expression of fibrinogen, and polymorphic variation within the fibrinogen genes is believed to alter the magnitude of this expression. The identification of the functional relevance of individual fibrinogen single nucleotide polymorphisms (SNPs) has been hindered by...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Cronjé, H. Toinét, Nienaber-Rousseau, Cornelie, Zandberg, Lizelle, de Lange, Zelda, Green, Fiona R., Pieters, Marlien
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5669433/
https://ncbi.nlm.nih.gov/pubmed/29099861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0187712
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