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Fibrinogen and clot-related phenotypes determined by fibrinogen polymorphisms: Independent and IL-6-interactive associations

Interleukin-6 (IL-6) induces the expression of fibrinogen, and polymorphic variation within the fibrinogen genes is believed to alter the magnitude of this expression. The identification of the functional relevance of individual fibrinogen single nucleotide polymorphisms (SNPs) has been hindered by...

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Bibliographische Detailangaben
Veröffentlicht in:PLoS One
Hauptverfasser: Cronjé, H. Toinét, Nienaber-Rousseau, Cornelie, Zandberg, Lizelle, de Lange, Zelda, Green, Fiona R., Pieters, Marlien
Format: Artigo
Sprache:Inglês
Veröffentlicht: Public Library of Science 2017
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5669433/
https://ncbi.nlm.nih.gov/pubmed/29099861
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0187712
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