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Production of bone marrow, liver, thymus (BLT) humanized mice on the C57BL/6 Rag2(−/−)γ(c)(−/−)CD47(−/−) background
C57BL/6 Rag2(−/−)γ(c)(−/−) CD47(−/−) triple-knockout mice engrafted with fetal human bone marrow, liver, thymus (TKO-BLT) not only develop high levels of multi-lineage hematopoiesis but also organized lymphoid tissues including mesenteric lymph nodes, splenic follicles and gut-associated lymphoid ti...
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| Main Authors: | , , , |
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| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2014
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4060441/ https://ncbi.nlm.nih.gov/pubmed/24769067 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jim.2014.04.008 |
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