Neonates with Cystic Fibrosis Have a Reduced Nasal Liquid pH; A Small Pilot Study

BACKGROUND: Disrupted HCO(3)(-) transport and reduced airway surface liquid (ASL) pH in cystic fibrosis (CF) may initiate airway disease. We hypothesized that ASL pH is reduced in neonates with CF. METHODS: In neonates with and without CF, we measured pH of nasal ASL. We also measured nasal pH in ol...

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Main Authors: Abou Alaiwa, Mahmoud H., Beer, Alison M., Pezzulo, Alejandro A., Launspach, Janice L., Horan, Rebecca A., Stoltz, David A., Starner, Timothy D., Welsh, Michael J., Zabner, Joseph
Format: Artigo
Sprog:Inglês
Udgivet: 2014
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060428/
https://ncbi.nlm.nih.gov/pubmed/24418186
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jcf.2013.12.006
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