T-helper 17 cell cytokines and interferon type I: partners in crime in systemic lupus erythematosus?

INTRODUCTION: A hallmark of systemic autoimmune diseases like systemic lupus erythematosus (SLE) is the increased expression of interferon (IFN) type I inducible genes, so-called IFN type I signature. Recently, T-helper 17 subset (Th17 cells), which produces IL-17A, IL-17F, IL-21, and IL-22, has bee...

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Main Authors: Brkic, Zana, Corneth, Odilia BJ, van Helden-Meeuwsen, Cornelia G, Dolhain, Radboud JEM, Maria, Naomi I, Paulissen, Sandra MJ, Davelaar, Nadine, van Hamburg, Jan Piet, van Daele, Paul L, Dalm, Virgil A, van Hagen, P Martin, Hazes, Johanna MW, Versnel, Marjan A, Lubberts, Erik
Format: Artigo
Language:Inglês
Published: BioMed Central 2014
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Research Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060204/
https://ncbi.nlm.nih.gov/pubmed/24598455
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/ar4499
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