Prevalence of interferon type I signature in CD14 monocytes of patients with Sjögren's syndrome and association with disease activity and BAFF gene expression

OBJECTIVE: To determine the prevalence of upregulation of interferon (IFN) type I inducible genes, the so called ‘IFN type I signature’, in CD14 monocytes in 69 patients with primary Sjögren's syndrome (pSS) and 44 healthy controls (HC) and correlate it with disease manifestations and expressio...

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Autors principals: Brkic, Zana, Maria, Naomi I, van Helden-Meeuwsen, Cornelia G, van de Merwe, Joop P, van Daele, Paul L, Dalm, Virgil A, Wildenberg, Manon E, Beumer, Wouter, Drexhage, Hemmo A, Versnel, Marjan A
Format: Artigo
Idioma:Inglês
Publicat: BMJ Group 2013
Matèries:
Clinical and Epidemiological Research
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3618683/
https://ncbi.nlm.nih.gov/pubmed/22736090
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1136/annrheumdis-2012-201381
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