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Degradable Cross-Linked Nanoassemblies as Drug Carriers for Heat Shock Protein 90 Inhibitor 17-N-Allylamino-17-demethoxy-geldanamycin

Cross-linked nanoassemblies (CNAs) with a degradable core were prepared for sustained release of 17-N-allylamino-17-demethoxygeldanamycin (17-AAG), a potent inhibitor of heat shock protein 90 (HSP90). The particle size of CNAs ranged between 100 and 250 nm, which changed depending on the cross-linki...

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Bibliografische gegevens
Hoofdauteurs: Ponta, Andrei, Akter, Shanjida, Bae, Younsoo
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: MDPI 2011
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060124/
https://ncbi.nlm.nih.gov/pubmed/27721325
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/ph4101281
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