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Alpha-mangostin inhibits intracellular fatty acid synthase and induces apoptosis in breast cancer cells

BACKGROUND: Fatty acid synthase (FAS) has been proven over-expressed in human breast cancer cells and consequently, has been recognized as a target for breast cancer treatment. Alpha-mangostin, a natural xanthone found in mangosteen pericarp, has a variety of biological activities, including anti-ca...

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Detalhes bibliográficos
Main Authors: Li, Ping, Tian, Weixi, Ma, Xiaofeng
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060095/
https://ncbi.nlm.nih.gov/pubmed/24894151
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1476-4598-13-138
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