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Alpha-mangostin induces endoplasmic reticulum stress and autophagy which count against fatty acid synthase inhibition mediated apoptosis in human breast cancer cells

BACKGROUND/AIMS: One of the most important metabolic hallmarks of breast cancer cells is enhanced lipogenesis. Increasing evidences suggest that fatty acid synthase (FAS) plays an important role in human breast cancer. Previously we discovered that alpha-mangostin showed apoptotic effect on human br...

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Detalhes bibliográficos
Publicado no:Cancer Cell Int
Main Authors: Huang, Wenyuan, Liang, Yan, Ma, Xiaofeng
Formato: Artigo
Idioma:Inglês
Publicado em: BioMed Central 2019
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6544980/
https://ncbi.nlm.nih.gov/pubmed/31164796
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12935-019-0869-z
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