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MRI of the tumor microenvironment in radiotherapy: perfusion, hypoxia and metabolism

The tumor microenvironment is characterized by hypoxia, low pH, and high interstitial fluid pressure. Hypoxic regions in tumors with low pO(2) levels can result in resistance to radiotherapy causing local failure. It would therefore be desirable to non-invasively measure pO(2) levels in the tumor pr...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Matsuo, Masayuki, Matsumoto, Shingo, Mitchell, James B., Krishna, Murali C., Camphausen, Kevin
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060050/
https://ncbi.nlm.nih.gov/pubmed/24931096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semradonc.2014.02.002
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