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MRI of the tumor microenvironment in radiotherapy: perfusion, hypoxia and metabolism

The tumor microenvironment is characterized by hypoxia, low pH, and high interstitial fluid pressure. Hypoxic regions in tumors with low pO(2) levels can result in resistance to radiotherapy causing local failure. It would therefore be desirable to non-invasively measure pO(2) levels in the tumor pr...

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Bibliografiske detaljer
Main Authors: Matsuo, Masayuki, Matsumoto, Shingo, Mitchell, James B., Krishna, Murali C., Camphausen, Kevin
Format: Artigo
Sprog:Inglês
Udgivet: 2014
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060050/
https://ncbi.nlm.nih.gov/pubmed/24931096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semradonc.2014.02.002
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