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MRI of the tumor microenvironment in radiotherapy: perfusion, hypoxia and metabolism

The tumor microenvironment is characterized by hypoxia, low pH, and high interstitial fluid pressure. Hypoxic regions in tumors with low pO(2) levels can result in resistance to radiotherapy causing local failure. It would therefore be desirable to non-invasively measure pO(2) levels in the tumor pr...

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Hlavní autoři: Matsuo, Masayuki, Matsumoto, Shingo, Mitchell, James B., Krishna, Murali C., Camphausen, Kevin
Médium: Artigo
Jazyk:Inglês
Vydáno: 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4060050/
https://ncbi.nlm.nih.gov/pubmed/24931096
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.semradonc.2014.02.002
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