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Mouse models of PI(3,5)P(2) deficiency with impaired lysosome function
The endo-lysosomal system and autophagy are essential components of macromolecular turnover in eukaryotic cells. The low-abundance signaling lipid PI(3,5)P(2) is a key regulator of this pathway. Analysis of mouse models with defects in PI(3,5)P(2) biosynthesis have revealed the unique dependence of...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
2014
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| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4059992/ https://ncbi.nlm.nih.gov/pubmed/24359958 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/B978-0-12-397926-1.00014-7 |
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