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NADPH oxidase-derived reactive oxygen species contribute to impaired cutaneous microvascular function in chronic kidney disease

Oxidative stress promotes vascular dysfunction in chronic kidney disease (CKD). We utilized the cutaneous circulation to test the hypothesis that reactive oxygen species derived from NADPH oxidase and xanthine oxidase impair nitric oxide (NO)-dependent cutaneous vasodilation in CKD. Twenty subjects,...

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Bibliographische Detailangaben
Hauptverfasser: DuPont, Jennifer J., Ramick, Meghan G., Farquhar, William B., Townsend, Raymond R., Edwards, David G.
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Physiological Society 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4059972/
https://ncbi.nlm.nih.gov/pubmed/24761000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00058.2014
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