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NADPH oxidase-derived reactive oxygen species contribute to impaired cutaneous microvascular function in chronic kidney disease

Oxidative stress promotes vascular dysfunction in chronic kidney disease (CKD). We utilized the cutaneous circulation to test the hypothesis that reactive oxygen species derived from NADPH oxidase and xanthine oxidase impair nitric oxide (NO)-dependent cutaneous vasodilation in CKD. Twenty subjects,...

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Detalhes bibliográficos
Main Authors: DuPont, Jennifer J., Ramick, Meghan G., Farquhar, William B., Townsend, Raymond R., Edwards, David G.
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2014
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4059972/
https://ncbi.nlm.nih.gov/pubmed/24761000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00058.2014
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