NADPH oxidase-derived reactive oxygen species contribute to impaired cutaneous microvascular function in chronic kidney disease

Oxidative stress promotes vascular dysfunction in chronic kidney disease (CKD). We utilized the cutaneous circulation to test the hypothesis that reactive oxygen species derived from NADPH oxidase and xanthine oxidase impair nitric oxide (NO)-dependent cutaneous vasodilation in CKD. Twenty subjects,...

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Autors principals: DuPont, Jennifer J., Ramick, Meghan G., Farquhar, William B., Townsend, Raymond R., Edwards, David G.
Format: Artigo
Idioma:Inglês
Publicat: American Physiological Society 2014
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Articles
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC4059972/
https://ncbi.nlm.nih.gov/pubmed/24761000
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/ajprenal.00058.2014
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