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A Ctf4 trimer couples the CMG helicase to DNA polymerase α in the eukaryotic replisome
Efficient duplication of the genome requires the concerted action of helicase and DNA polymerases at replication forks(1), to avoid stalling of the replication machinery and consequent genomic instability(2-4). In eukaryotes, the physical coupling between helicase and DNA polymerases remains poorly...
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| Main Authors: | , , , , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2014
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4059944/ https://ncbi.nlm.nih.gov/pubmed/24805245 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature13234 |
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