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The validation of a novel method combining both HER2 immunohistochemistry and HER2 dual-colour silver in situ hybridization on one slide for gastric carcinoma testing

BACKGROUND: HER2 status assessment is a prerequisite for the establishment of an appropriate treatment strategy in gastric cancer. Gastric cancers are very heterogeneous and separate evaluations of gene amplification and protein expression lead to uncertainties in localizing distinct clones and are...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Werner, Dominique, Battmann, Achim, Steinmetz, Kristina, Jones, Tobin, Lamb, Tiffany, Martinez, Michele, Altmannsberger, Hans-Michael, Al-Batran, Salah-Eddin
Format: Artigo
Sprache:Inglês
Veröffentlicht: BioMed Central 2014
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4059883/
https://ncbi.nlm.nih.gov/pubmed/24906218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-12-160
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