The validation of a novel method combining both HER2 immunohistochemistry and HER2 dual-colour silver in situ hybridization on one slide for gastric carcinoma testing

BACKGROUND: HER2 status assessment is a prerequisite for the establishment of an appropriate treatment strategy in gastric cancer. Gastric cancers are very heterogeneous and separate evaluations of gene amplification and protein expression lead to uncertainties in localizing distinct clones and are...

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Main Authors: Werner, Dominique, Battmann, Achim, Steinmetz, Kristina, Jones, Tobin, Lamb, Tiffany, Martinez, Michele, Altmannsberger, Hans-Michael, Al-Batran, Salah-Eddin
Formato: Artigo
Idioma:Inglês
Publicado: BioMed Central 2014
Assuntos:
Research
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4059883/
https://ncbi.nlm.nih.gov/pubmed/24906218
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1479-5876-12-160
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