Evaluation of Immunohistochemistry-Equivocal (2+) HER2 Gene Status in Invasive Breast Cancer by Silver DNA in Situ Hybridization (SISH) and its Association with Clinicopathological Variables

BACKGROUND AND OBJECTIVE: Determination of HER2 gene is crucial in breast carcinoma management and prognosis, as HER2 alterations are linked to a shorter disease-free period, overall survival and resistance to tamoxifen anti-estrogen therapy and other chemotherapy regimens, regardless of the nodal o...

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Veröffentlicht in:Iran J Pathol
Hauptverfasser: A. Musa, Zaidoon, J. Qasim, Ban, A.K. Al Shaikhly, A.Wahab
Format: Artigo
Sprache:Inglês
Veröffentlicht: Iranian Society of Pathology 2017
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Original Article
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC5938719/
https://ncbi.nlm.nih.gov/pubmed/29760748
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