The Quaternary Lidocaine Derivative QX-314 Produces Long-Lasting Intravenous Regional Anesthesia in Rats

BACKGROUND: The lidocaine derivative, QX-314, produces long-lasting regional anesthesia in various animal models. We designed this study to examine whether QX-314 could produce long-lasting intravenous regional anesthesia (IVRA) in a rat model. METHODS: IVRA was performed on tail of rats. EC(50) (me...

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Autores principales: Zhao, Yi, Zhou, Cheng, Liu, Jin, Liang, Peng, Liao, Daqing, Chen, Yanfang, Chen, Xiangdong
Formato: Artigo
Lenguaje:Inglês
Publicado: Public Library of Science 2014
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Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4059684/
https://ncbi.nlm.nih.gov/pubmed/24932639
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0099704
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