The quaternary lidocaine derivative QX-314 in combination with bupivacaine for long-lasting nerve block: Efficacy, toxicity, and the optimal formulation in rats

OBJECTIVE: The quaternary lidocaine derivative (QX-314) in combination with bupivacaine can produce long-lasting nerve blocks in vivo, indicating potential clinical application. The aim of the study was to investigate the efficacy, safety, and the optimal formulation of this combination. METHODS: QX...

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Detalhes bibliográficos
Publicado no:PLoS One
Main Authors: Yin, Qinqin, Li, Jun, Zheng, Qingshan, Yang, Xiaolin, Lv, Rong, Ma, Longxiang, Liu, Jin, Zhu, Tao, Zhang, Wensheng
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2017
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC5363931/
https://ncbi.nlm.nih.gov/pubmed/28334014
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0174421
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