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Multiplex Assay for Live-Cell Monitoring of Cellular Fates of Amyloid-β Precursor Protein (APP)

Amyloid-β precursor protein (APP) plays a central role in pathogenesis of Alzheimer's disease. APP has a short half-life and undergoes complex proteolytic processing that is highly responsive to various stimuli such as changes in cellular lipid or energy homeostasis. Cellular trafficking of APP...

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Hlavní autoři: Merezhko, Maria, Muggalla, Pranuthi, Nykänen, Niko-Petteri, Yan, Xu, Sakha, Prasanna, Huttunen, Henri J.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2014
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4059622/
https://ncbi.nlm.nih.gov/pubmed/24932508
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0098619
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