Wordt geladen...

Amyloid precursor protein (APP) regulates synaptic structure and function

The amyloid precursor protein (APP) plays a critical role in Alzheimer’s disease (AD) pathogenesis. APP is proteolytically cleaved by β- and γ-secretases to generate the amyloid β-protein (Aβ), the core protein component of senile plaques in AD. It is also cleaved by α-secretase to release the large...

Volledige beschrijving

Bewaard in:
Bibliografische gegevens
Hoofdauteurs: Tyan, Sheue-Houy, Shih, Ann Yu-Jung, Walsh, Jessica J., Murayama, Hiroko, Sarsoza, Floyd, Ku, Lawrence, Eggert, Simone, Hof, Patrick R., Koo, Edward H., Dickstein, Dara L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2012
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3538857/
https://ncbi.nlm.nih.gov/pubmed/22884903
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.mcn.2012.07.009
Tags: Voeg label toe
Geen labels, Wees de eerste die dit record labelt!