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Loss of TRPM2 function protects against irradiation-induced salivary gland dysfunction

Xerostomia as a result of salivary gland damage is a permanent and debilitating side effect of radiotherapy for head and neck cancers. Effective treatments for protecting, or restoring, salivary gland function are not available. Here we report that irradiation treatment leads to activation of the ca...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Liu, Xibao, Cotrim, Ana, Teos, Leyla, Zheng, Changyu, Swaim, William, Mitchell, James, Mori, Yasuo, Ambudkar, Indu
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2013
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4059199/
https://ncbi.nlm.nih.gov/pubmed/23443543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/ncomms2526
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