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Adenovirus-mediated hAQP1 expression in irradiated mouse salivary glands causes recovery of saliva secretion by enhancing acinar cell volume decrease

Head and neck irradiation (IR) during cancer treatment causes by-stander effects on the salivary glands leading to irreversible loss of saliva secretion. The mechanism underlying loss of fluid secretion is not understood and no adequate therapy is currently available. Delivery of an adenoviral vecto...

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Foilsithe in:Gene Ther
Main Authors: Teos, LY, Zheng, C-Y, Liu, X, Swaim, WD, Goldsmith, CM, Cotrim, AP, Baum, BJ, Ambudkar, IS
Formáid: Artigo
Teanga:Inglês
Foilsithe: 2016
Ábhair:
Rochtain Ar Líne:https://ncbi.nlm.nih.gov/pmc/articles/PMC5798877/
https://ncbi.nlm.nih.gov/pubmed/26966862
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/gt.2016.29
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